
Opleiding: Course Crash course blast
Leerdoel
The course Crash course blast is provided by the Institute for Life Science & Technology, Hanze University of Applied Sciences Groningen.
Crash course blast is designed to get you beyond the simple ‘copy, paste & go’ approach that is usually employed by life science researchers, when they want to find sequences with similarity to their own sequence of interest. This course will deal with the theory and practice of blast in all its varieties.
After attending the course:
- you have an understanding of the Blast algorithm, the different programs, their applications and settings;
- you will be able to intelligently choose a blast program and search strategy that is most likely to answer your questions.
Doelgroep
Crash course blast is intended for anyone working with biological sequence data. This includes PhD students, master and bachelor students, post-docs, lab technicians and other life science professionals.
Programma
The subjects that will be dealt with are:
- all blast program varieties (blastp, blastn, blastx, tblastn, tblastx)
- scoring matrices
- blast statistics
- blast databases
- use of blast settings to increase speed, sensitivity or specificity
- special blast(-like) applications: PSI-blast, PHI-blast, RPS-blast
- designing (blast) search strategies for a wide range of research questions
Toelatingseisen
Prerequisite knowledge
Basic computer skills and the core themes of molecular biology theory: DNA, RNA, protein, transcription, translation
