Vergelijkbare opleidingen
Opleiding: Course Sequence comparison and blast
Leerdoel
The course Sequence comparison and blast is provided by the Institute for Life Science & Technology, Hanze University of Applied Sciences Groningen.
The course Sequence comparison and blast is designed to get you beyond the simple ’copy, paste & go’ approach that is usually employed by life science researchers, when they want to find sequences with similarity to their own sequence of interest or when they want to investigate other specific sequence properties and elements.
This course will deal with the theory and practice of blast in all its varieties and with a selected set of other sequence comparison tools. After attending this course you will be able to intelligently choose a blast program and search strategy that is most likely to answer your questions, or maybe another program entirely that is more suited to the specific questions at hand. This course overlaps the course “Crash course blast” but is broader in its overview of sequence analysis tools besides Blast.
Doelgroep
The course is intended for anyone working with biological sequence data, who wish to improve their grasp of and skills with sequence analysis tools. This includes PhD students, master and bachelor students, post-docs, lab technicians and other life science professionals.
Programma
The subjects that will be dealt with are:
- pairwise sequence alignment
- scoring matrices, blast databases, blast statistics
- all blast program varieties (blastp, blastn, blastx, tblastn, tblastx)
- use of blast settings to increase speed, sensitivity or specificity
- special blast(-like) applications: PSI-blast, PHI-blast, RPS-blast
- patterns and profiles; their databases and applications
- designing (blast) search strategies for a wide range of research questions
- a description of how to set up a blast server and to create your own blast databases
Toelatingseisen
Prerequisite knowledge
Basic computer skills and the core themes of molecular biology theory: DNA, RNA, protein, transcription, translation.
Opleiding kerngegevens